High fat diets and depression: a look in mice

Only a few weeks ago I looked at a study on fast food consumption and depression, and only a few days ago I talked about a brand new study looking at high fat diets and protection from heart attack damage. And today, we’ve got another study on high fat diet, this time in mice, and depressive-like behavior. What is the effect of a high fat diet? Well, it appears to be getting more complicated with each new study.

But in this study, at least, it looks like diet-induced obesity might produce depressive-like effects in mice. But how the diet is doing that is not so well defined.

Sharma and Fulton. “Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry” International Journal of Obesity, 2012.

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