Eating less may keep the mind young, according to Italian scientists who reported Monday they have discovered the molecular process by which a strict diet may save the brain from the ravages of age.
The research, published in the US journal the Proceedings of the National Academy of Sciences, is based on a study of mice that were fed a diet of about 70 percent of the food they normally consumed.
Scientists found the calorie-restricted diet triggered a protein molecule, CREB1, that activates a host of genes linked to longevity and good brain function.
"Our hope is to find a way to activate CREB1, for example through new drugs, so to keep the brain young without the need of a strict diet," said lead author Giovambattista Pani, researcher at the Institute of General Pathology, Faculty of Medicine at the Catholic University of Sacred Heart in Rome.
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