Sunday, November 13, 2011

Experimental drug takes pounds off overweight monkeys

An experimental drug helped obese monkeys lose 11 percent of their extra weight in a month, a promising sign in the hunt for obesity drugs that could apply to humans, US researchers said.

The drug, known as Adipotide, works by attacking the blood supply of a certain kind of fat, known as white adipose tissue, that tends to accumulate under the skin and around the belly.

Most other obesity drugs focus on either reducing appetite, boosting metabolism or preventing the absorption of fat.

The research, led by the University of Texas MD Anderson Cancer Center, offers a potential new pathway for treatment and has also shown effects in mice who lost 30 percent of their body weight during treatment.

"Most drugs against obesity fail in transition between rodents and primates," said co-senior author Renata Pasqualini, whose study appears in the journal Science Translational Medicine.



Read more: http://www.nydailynews.com/life-style/health/experimental-drug-takes-pounds-overweight-monkeys-article-1.976217#ixzz1dRGUJuIp

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